Cancer BiologybioRxivPreprint
PREDICTIVE IMMUNE CHECKPOINT BLOCKADE CLASSIFIERS DISTINGUISHING MONO- VERSUS COMBINATION THERAPY REQUIREMENT
O. Krijgsman, K. Kemper, J. Boshuizen…·D. S. Peeper
This paper develops two genetic signatures, InTumor and ExTumor, to predict immune checkpoint blockade response in melanoma patients, enabling stratification for monotherapy or combination therapy.
DOI 10.1101/2020.07.14.202408