An intramolecular scrambling path controlled by a gatekeeper in Xkr8 phospholipid scramblase
T. Sakuragi, R. Kanai, A. Tsutsumi, H. Narita, E. Onishi, T. Miyazaki, T. Baba, A. Nakagawa, M. Kikkawa, C. Toyoshima, S. Nagata
The paper determines the structure of Xkr8-Basigin phospholipid scramblase at 3.8 Å resolution, revealing a gatekeeper tryptophan residue essential for phospholipid scrambling.
bioRxiv · May 6, 2021Biochemistry