Author

R. L. Mueller

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 4

Signature Assays, Organisms & Methods

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Research Focus:development & morphogenesis· 2 Approach:experimental assay· 2 Organism:multiple species· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Assay:imaging· 1

Frequent Co-Authors

A. N. Adams· 2 shared B. J. Smith· 1 shared C. E. Cressler· 1 shared D. S. Siegel· 1 shared M. A. Butler· 1 shared M. W. Itgen· 1 shared R. A. Chong· 1 shared R. D. Denton· 1 shared

Activity by Year

2021-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 11 mutual co-author links

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2 shared papersEvolutionary Biology

A. N. Adams

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Author profile →

4 papers

Recent·Most cited

Gigantic Animal Cells Suggest Organellar Scaling Mechanisms Across a 50-fold Range in Cell Volume

A. N. Adams, B. J. Smith, T. J. Raad, R. L. Mueller

The paper examines organellar scaling in amphibian enterocytes across a 50-fold cell volume range, finding proportional volume increases in nuclei, mitochondria, and other organelles, suggesting consistent proteome concentration despite varying metabolic demands.

bioRxiv · Aug 30, 2023Evolutionary Biology

Gigantic Genomes of Salamanders Indicate Body Temperature, not Genome Size, is the Driver of Global Methylation and 5-Methylcytosine Deamination in Vertebrates

A. N. Adams, R. D. Denton, R. L. Mueller

The paper measures CpG methylation and CpG dinucleotide levels in salamanders with large genomes and compares them to endo- and ectothermic vertebrates, finding no correlation between genome size and methylation levels.

bioRxiv · Sep 27, 2021Evolutionary Biology

Genome size drives morphological evolution in organ-specific ways

M. W. Itgen, D. S. Siegel, S. K. Sessions, R. L. Mueller

This study shows that genome size affects heart and liver morphology in salamanders, with structural changes in these organs linked to evolutionary increases in genome size.

bioRxiv · Aug 17, 2021Evolutionary Biology

Metamorphosis imposes variable constraints on genome expansion

R. L. Mueller, C. E. Cressler, R. S. Schwarz, R. A. Chong, M. A. Butler

The paper investigates how metamorphosis constrains genome expansion in salamanders, finding that more extensive and synchronous remodeling imposes stricter limits on genome size.

bioRxiv · May 5, 2021 · PreprintEvolutionary Biology