Hexarelin exerts neuroprotective and antioxidant effects against hydrogen peroxide-induced toxicity through the modulation of MAPK and PI3K/Akt patways in Neuro-2A cells.
R. Meanti, L. Rizzi, E. Bresciani, L. Molteni, V. Locatelli, S. Coco, R. J. Omeljaniuk, A. Torsello
This study shows hexarelin protects Neuro-2A cells from H2O2-induced toxicity by modulating MAPK and PI3K/Akt pathways, reducing apoptosis and oxidative stress.
bioRxiv · Nov 16, 2020Pharmacology & Toxicology