Condensation of PRPP amidotransferase by phase separation promotes de novo purine synthesis through intermolecular intermediate channeling in yeast
M. Takaine, R. Morita, Y. Yoshinari, T. Nishimura
This study shows that PRPP amidotransferase forms condensates in yeast under purine deprivation, enhancing de novo purine synthesis through intermolecular intermediate channeling.
bioRxiv · Jun 5, 2023Cell Biology