Does Antibody Stabilize the Ligand Binding in GP120 of HIV-1 Envelope Protein? Evidence from MD Simulation
V. Pandey, R. K. Tiwari, R. P. Ojha, K. D. Dubey
The paper uses MD simulations to investigate how an antibody affects the conformational flexibility of gp120 induced by a CD4-mimetic inhibitor, showing enhanced NBD-557 affinity.
bioRxiv · Apr 1, 2019 · PreprintBiochemistry