R. Starke

Database-independent analysis of probable post-translational modifications of soil proteins across ecosystems

The paper uses a database-independent method to identify probable post-translational modifications in soil proteins across different ecosystems, finding similar PTMs across ecosystems but significant changes in some mass intervals.

Explorative meta-analysis of 417 extant archaeal genomes to predict their contribution to the total microbiome functionality

The paper predicts archaea's contribution to global microbiome functionality by analyzing 417 archaeal genomes and finding functional redundancy patterns.

Meta-analysis of 139 extant Tara ocean metagenomes to unveil the relationship between taxonomy and functionality in prokaryotes inhabiting aquatic ecosystems

The paper analyzes 139 Tara Ocean metagenomes to explore the relationship between prokaryotic taxonomy and functionality, finding that functional richness increases with species richness and diversity.

Gene copy normalization of the 16S rRNA gene cannot outweigh the methodological biases of sequencing

This study shows that gene copy normalization (GCN) of the 16S rRNA gene only partially corrects sequencing biases in low-diversity communities, suggesting GCN may not reliably improve accuracy in most cases.

The total fungal microbiome functionality

The paper predicts the total fungal microbiome functionality using 377 annotated fungal genomes, finding 42.4 million functions with only 0.06% known, highlighting the need for new methods to explore rare functions.