Real Time Normalization of Fast Photochemical Oxidation of Proteins Experiments by Inline Adenine Radical Dosimetry
J. S. Sharp, S. K. Misra, J. J. Persoff, R. W. Egan, S. R. Weinberger
This paper introduces real-time radical dosimetry for FPOP experiments to normalize hydroxyl radical concentration, enabling reproducible protein footprinting across varying buffer conditions.
bioRxiv · Jun 26, 2018Biochemistry