Pleiotropic effects of a recessive COL1A2 mutation occurring in a mouse model of severe osteogenesis imperfecta
Michelangelo Corcelli, Rachel L. Sagar, Ellen Petzendorfer, Mohammad Mehedi Hasan, Hilda I. de Vries, Fleur Stephanie van Dijk, Anna Louise David, Pascale V. Guillot
This study investigates the pleiotropic effects of a recessive COL1A2 mutation in OIM mice, revealing mechanisms of bone fragility in severe osteogenesis imperfecta.
bioRxiv · Feb 15, 2024 · PreprintGenetics