EXPERIMENTAL KINETIC MECHANISM OF P53 CONDENSATION-AMYLOID AGGREGATION
Silvia Susana Borkosky, Ramon Peralta-Martinez, Alicia Armella-Sierra, Sebastián Esperante, Leonardo Lizárraga, Javier García‐Pardo, Salvador Ventura, Ignacio Enrique Sanchez, Gonzalo de Prat Gay
This paper investigates the kinetic mechanism of p53 condensation and amyloid aggregation, revealing a pathway from coacervates to fibrils and suggesting therapeutic targets for p53-related cancers.
Biophysical Journal · Apr 11, 2025Peer-reviewedBiophysics