GALE-dependent glycoproteome remodelling is a determinant of oncogenic RAS transformation
Frauke Stölting, Rita Vesce, César Rodríguez-Santana, Marina Ciscar, Alberto Delaidelli, Qiaochu Lin, Christian Ballmeyer, Sophie Chan, Ramona Lesch, Ruitong Li, Abhimanyu DasGupta, Bin Yu, Daniel Picard, Vithusan Suppiyar, Francesco Casini, , Jonathan K. M. Lim
This study identifies GALE as a key regulator of glycoproteome remodelling in RAS-driven cancer, showing its role in sialylation and tumorigenicity.
bioRxiv · Jun 23, 2026 · PreprintCancer Biology