Ruitong Li

High-Throughput Machine Learning-Aided Antibody Discovery for Cell Surface Antigens

The paper develops a synthetic Fab yeast display library integrated with machine learning to discover antibodies against cell surface antigens, yielding hundreds of validated antibodies and a public dataset.

GALE-dependent glycoproteome remodelling is a determinant of oncogenic RAS transformation

This study identifies GALE as a key regulator of glycoproteome remodelling in RAS-driven cancer, showing its role in sialylation and tumorigenicity.

scDiffEq: drift-diffusion modeling of single-cell dynamics with neural stochastic differential equations

scDiffEq models single-cell dynamics using neural stochastic differential equations, improving trajectory reconstruction and fate prediction in hematopoiesis.

Transcriptional survey of peripheral blood links lower oxygen saturation during sleep with reduced expressions of CD1D and RAB20 that is reversed by CPAP therapy

The paper examines gene expression in blood cells linked to sleep apnea traits, identifying CD1D and RAB20 expression changes reversed by CPAP treatment.

Epigenome-wide association analysis of daytime sleepiness in the Multi-Ethnic Study of Atherosclerosis reveals African-American specific associations

The paper identifies DNA methylation sites associated with daytime sleepiness in African Americans using epigenome-wide association analysis in the Multi-Ethnic Study of Atherosclerosis.