Extensive profiling of transcription factors in postmortem brains defines genomic occupancy in disease-relevant cell types and links TF activities to neuropsychiatric disorders
Jacob M. Loupe, Ashlyn G. Anderson, Lindsay F. Rizzardi, Iván Rodríguez-Nunez, Belle A. Moyers, Katie Trausch‐Lowther, Rashmi Jain, William E. Bunney, Blynn G. Bunney, Preston M. Cartagena, Adolfo Sequeira, Stanley J. Watson, Huda Akil, Gregory M. Cooper, R Myers
The paper generates a multi-omic resource of TF binding maps in human brain tissues and links TF activities to neuropsychiatric disorder risk variants.
Nature Neuroscience · Jun 3, 2024Peer-reviewedGenomics