Penalized Logistic Regression Analysis for Genetic Association Studies of Binary Phenotypes
Ying Yu, Siyuan Chen, Samantha Jean Jones, Rawnak Hoque, Olga Vishnyakova, Angela R Brooks-Wilson, Brad McNeney
The paper introduces a penalized logistic regression method using log-F priors to reduce bias in genetic association studies with binary phenotypes, showing lower bias and mean squared error in simulations.
Human Heredity · Jan 1, 2022Peer-reviewedGenetics