BESTish: A Diffusion-Approximation Framework for Inferring Selection and Mutation in Clonal Hematopoiesis
Ren-Yi Wang, Khanh Ngoc Dinh, Keito Taketomi, Guodong Pang, Katherine Y. King, Marek Kimmel
BESTish infers mutation fitness, mutation rate, and environmental strength in clonal hematopoiesis using a diffusion-approximation framework applied to VAF datasets.
bioRxiv · Feb 5, 2026 · PreprintBioinformatics