Author

Katherine Y. King

Baylor College of MedicineORCID 0000-0002-5093-6005Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Cell Biology· 1 Genetic & Genomic Medicine· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Assay:whole-genome sequencing· 3 Assay:bulk RNA-seq· 2 Organism:human· 2 Organism:mouse· 2 Research Focus:variant calling· 2 Assay:ATAC-seq· 1 Approach:Bayesian inference· 1

Frequent Co-Authors

Alejandra G. Martell· 1 shared Alex CaganiD· 1 shared Alexandre F. CariseyiD· 1 shared Aniko SaboiD· 1 shared Anna G. Guzman· 1 shared Anton James EnrightiD· 1 shared Antony RodrigueziD· 1 shared Blake VuocoloiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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1 shared paperGenomics

Alejandra G. Martell

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Author profile →

4 papers

Recent·Most cited

Integrated Clinical-Genomic Reanalysis Identifies Diagnostic Gaps and Candidate Genes in a Pediatric Rare Disease Cohort

Hyunjung Gu, Aniko Sabo, Sharayu V. Jangam, H Hashimoto, Christina Y. Miyake, Bo Yuan, Charul Gijavanekar, Eric Venner, Viktoriya Korchina, Sarah H. Elsea, Donna Marie Muzny, Elizabeth A. Mizerik, Blake Vuocolo, Poyyapakkam R. Srivaths, Lisa Forbes Satter, , Katherine Y. King

medRxiv · Sep 30, 2026 · PreprintGenetic & Genomic Medicine

BESTish: A Diffusion-Approximation Framework for Inferring Selection and Mutation in Clonal Hematopoiesis

Ren-Yi Wang, Khanh Ngoc Dinh, Keito Taketomi, Guodong Pang, Katherine Y. King, Marek Kimmel

BESTish infers mutation fitness, mutation rate, and environmental strength in clonal hematopoiesis using a diffusion-approximation framework applied to VAF datasets.

bioRxiv · Feb 5, 2026 · PreprintBioinformatics

Let-7 restrains an oncogenic circuit in AT2 cells to prevent fibrogenic cell intermediates in pulmonary fibrosis

Matthew J. Seasock, Md Shafiquzzaman, Maria Elisa Ruiz Echartea, Rupa S. Kanchi, Brandon T. Tran, Lukas Mikolaj Simon, Matthew D. Meyer, Phillip A. Erice, Shivani L. Lotlikar, Stephanie C. Wenlock, Scott A. Ochsner, Anton James Enright, Alexandre F. Carisey, Freddy Romero, Iván O. Rosas, , Antony Rodriguez

This study identifies let-7 as a regulator of AT2 cell differentiation and fibrosis prevention by controlling oncogenic networks and epigenetic changes.

Nature Communications · May 10, 2025Peer-reviewedCell Biology

Clonal dynamics and somatic evolution of haematopoiesis in mouse

Chiraag Deepak Kapadia, Nicholas Williams, Kevin J. Dawson, Caroline J. Watson, Matthew J. Yousefzadeh, Duy Tri Le, Kudzai Nyamondo, Sreeya Kodavali, Alex Cagan, Sarah M. Waldvogel, Xiaoyan Zhang, Josephine De La Fuente, Daniel A. Leongamornlert, Emily Mitchell, Marcus Alexander Florez, , Jyoti Nangalia

This study examines clonal dynamics and somatic evolution in mouse haematopoiesis, finding that stem cells accrue mutations at a rate similar to human progenitors and exhibit distinct age-related patterns.

Nature · Mar 5, 2025Peer-reviewedGenomics