Precision neoantigen discovery using large-scale immunopeptidomes and composite modeling of MHC peptide presentation
Rachel Marty Pyke, Dattatreya Mellacheruvu, Steven Dea, Charles W. Abbott, Simo V. Zhang, Nick A. Phillips, Jason Harris, Gabor T. Bartha, Sejal Desai, Rena McClory, John S. West, Michael P. Snyder, Richard Chen, Sean Michael Boyle
This paper introduces SHERPA, a pan-allelic MHC-peptide prediction algorithm, which improves neoantigen discovery by integrating immunopeptidomics data and composite modeling.
Molecular & Cellular Proteomics · Jan 1, 2021Peer-reviewedBioinformatics