RNAseq analysis of rodent spaceflight experiments is confounded by sample collection techniques
San-Huei Lai Polo, Amanda Saravia-Butler, Valery Boyko, Marie T. Dinh, Yi‐Chun Chen, Homer W. Fogle, Sigrid S. Reinsch, Shayoni Ray, Kaushik Chakravarty, Oana Marcu, Rick B. Chen, Sylvain V. Costes, Jonathan M. Galazka
The paper shows that RNAseq analysis of rodent spaceflight experiments is confounded by sample collection and preservation techniques, with preservation effects overshadowing spaceflight effects.
iScience · Jan 1, 2020Peer-reviewedSystems Biology