Author

Ridge Dershem

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetics· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:gene regulatory network inference· 1 Assay:GWAS summary statistics· 1 Assay:whole-exome sequencing· 1

Frequent Co-Authors

David J. CareyiD· 2 shared Gerda E. BreitwieseriD· 2 shared Janet D. RobishawiD· 2 shared Raghu Prasad Rao MetpallyiD· 2 shared Andrea CippitelliiD· 1 shared Bianca Fakhoury· 1 shared Diane T. SmelseriD· 1 shared Gloria BrunoriiD· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersNeuroscience

David J. CareyORCID

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Author profile →

2 papers

Recent·Most cited

Rare GPR37L1 variants reveal potential roles in anxiety and migraine disorders

Gerda E. Breitwieser, Andrea Cippitelli, Yingcai Wang, Oliver B. Pelletier, Ridge Dershem, Jianning Wei, Lawrence Toll, Bianca Fakhoury, Gloria Brunori, Raghu Prasad Rao Metpally, David J. Carey, Janet D. Robishaw

The paper identifies rare GPR37L1 variants associated with anxiety and migraine using computational analysis and functional experiments in cells and mice.

bioRxiv · Jul 5, 2023 · PreprintNeuroscience

Rare Variant Pathogenicity Triage and Inclusion of Synonymous Variants Improves Analysis of Disease Associations

Ridge Dershem, Raghu Prasad Rao Metpally, Kirk Jeffreys, Sarath B. Krishnamurthy, Diane T. Smelser, Michal Hershfinkel, David J. Carey, Janet D. Robishaw, Gerda E. Breitwieser

The paper uses rare variant analyses to identify disease associations for understudied GPCRs, finding that rare synonymous variants can contribute to disease associations similar to loss-of-function and missense variants.

Journal of Biological Chemistry · Oct 18, 2019Peer-reviewedGenetics