Cell BiologybioRxivPreprint
Maturation-dependent complement production and C3 processing in human retinal pigment epithelium cells
Juliane Schikora, Antonia Nickel, Jasmin Bergert…·Diana Pauly
This study compares immature and mature iPSC-RPE and ARPE-19 cells, showing that mature cells secrete active complement forms and process C3 differently, impacting local complement activation.
DOI 10.1101/2025.02.05.636432