Searching sequence databases for functional homologs using profile HMMs: how to set bit score thresholds?
Jaya Srivastava, Ritu Hembrom, Ankita Kumawat, Petety V. Balaji
The paper discusses methods to customize functional homolog searches using profile HMMs and evaluates bit score thresholds through case studies.
bioRxiv · Jun 24, 2021 · PreprintBioinformatics