Homocysteine thiolactone from translation proofreading is an endogenous ligand for cell-cell signaling by the receptor SdiA
Lorenzo Eugenio Leiva, Roberto Zuniga, Gregory J. Phillips, Michael Ibba
The paper identifies homocysteine thiolactone (HTL) as an endogenous ligand for the SdiA receptor, showing it modulates bacterial communication by affecting growth and gene expression.
mBio · Jul 16, 2026Peer-reviewedMolecular Biology