Evidence that low socioeconomic position accentuates genetic susceptibility to obesity
Jessica Tyrrell, Andrew R Wood, Ryan M Ames, Hanieh Yaghootkar, Robin N. Beaumont, Samuel E. Jones, Marcus A Tuke, Katherine S. Ruth, Rachel M Freathy, George Davey Smith, Stéphane Joost, Idris Guessous, Anna Murray, David P. Strachan, Zoltán Kutalik, , Timothy M Frayling
The paper tests if socioeconomic position amplifies genetic risk for obesity using UK Biobank data and finds gene-environment interactions with socioeconomic deprivation.
bioRxiv · Sep 13, 2016 · PreprintGenetics