Celsr1a is essential for tissue homeostasis and onset of aging phenotypes in the zebrafish.
Chunmei Li, Carrie L. Barton, Katrin Henke, Jake Daane, Stephen B. Treaster, Joana Caetano‐Lopes, Robyn L Tanguay, Matthew P. Harris
This study identifies celsr1a as essential for tissue homeostasis and aging onset in zebrafish, showing its role in maintaining progenitor cells and that caloric restriction can mitigate its effects.
eLife · Jan 27, 2020Peer-reviewedDevelopmental Biology