Mapping the drivers of within-host pathogen evolution using massive data sets
Duncan S. Palmer, Isaac Turner, Sarah J. Fidler, John Frater, Dominique Goedhals, Philip Goulder, Kuan‐Hsiang Gary Huang, Annette Oxenius, Rodney Phillips, Roger Shapiro, Cloete van Vuuren, Angela Ruth McLean, Gil McVean
The paper develops a Bayesian method to detect host influences on pathogen evolution using large datasets, demonstrating improved precision in identifying HLA-induced selection in HIV-1.
Nature Communications · Jul 9, 2019Peer-reviewedGenetics