The cell cycle regulates cell-penetrating peptide cytosolic uptake via differential expression of KCNH1 potassium channel
Francisco Tomás Ribeiro, Ali Hallaj, Roger Mora, Anita Lüthi, Evgeniya Trofimenko, Christian Widmann
This study identifies KCNH1 as a cell cycle-regulated potassium channel that modulates plasma membrane potential, thereby influencing the efficiency of cell-penetrating peptide (CPP) direct translocation.
bioRxiv · Sep 6, 2026 · PreprintCell Biology