Simultaneous Brain, Brainstem and Spinal Cord pharmacological-fMRI reveals endogenous opioid network interactions mediating attentional analgesia
Valeria Oliva, Ron Hartley-Davies, Rosalyn Moran, Anthony E Pickering, Jonathan CW Brooks
The paper uses pharmacological-fMRI to show that attentional analgesia in humans is mediated by opioidergic pathways from ACC to PAG and RVM, which suppress spinal nociceptive activity.
eLife · Jan 26, 2022Peer-reviewedNeuroscience