Author

Rong Han

Tsinghua University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 4

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Assay:protein structure· 2 Approach:statistical model· 2 Approach:deep learning· 1 Approach:diffusion model· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Assay:metagenomics· 1

Frequent Co-Authors

Jianzhu MaiD· 2 shared Peidong ZhangiD· 2 shared Bo YangiD· 1 shared Chunmei ShiiD· 1 shared Fengya Feng· 1 shared Hawen Han· 1 shared Jiangfeng LiuiD· 1 shared Jingyuan WuiD· 1 shared

Activity by Year

2021-2025 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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2 shared papersBioinformatics

Jianzhu MaORCID

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Author profile →

4 papers

Recent·Most cited

Global profiling of the proteome and acetylome in mice with abdominal aortic aneurysms

Luyao Zhang, Bo Yang, Tao Ding, Yaling Zhao, Yehong Yang, Xiaoyue Tang, Yue Wu, Qiaochu Wang, Zhiyi Zhang, Chunmei Shi, Rong Han, Xutong Zhang, Jiangfeng Liu, Juntao Yang

This study identifies potential therapeutic targets for abdominal aortic aneurysms by analyzing proteomic and acetylomic changes in a mouse model.

ACS Omega · Nov 10, 2025Peer-reviewedBioinformatics

SpecLig: Energy-Guided Hierarchical Model for Target-Specific 3D Ligand Design

Peidong Zhang, Rong Han, Xiangzhe Kong, Ting Chen, Jianzhu Ma

SpecLig generates target-specific ligands with high affinity and specificity by integrating hierarchical modeling and energy guidance, improving therapeutic potential and reducing off-target risks.

bioRxiv · Nov 6, 2025 · PreprintBioinformatics

Rag2Mol: Structure-based drug design based on Retrieval Augmented Generation

Peidong Zhang, Xingang Peng, Rong Han, Ting Chen, Jianzhu Ma

This paper introduces Rag2Mol methods for structure-based drug design using retrieval-augmented generation, producing drug candidates with better binding affinities and drug-likeness than existing models.

Briefings in Bioinformatics · May 1, 2025Peer-reviewedBioinformatics

SARS-CoV-2 triggered excessive inflammation and abnormal energy metabolism in gut microbiota

Tuoyu Zhou, Yufei Zeng, Jingyuan Wu, Junfeng Li, Jun Yan, Wenbo Meng, Hawen Han, Fengya Feng, Jufang He, Shuai Zhao, Ping Zhou, Ying Wu, Yanling Yang, Rong Han, Weiling Jin, , Xiangkai Li

This study analyzes gut microbiota changes in COVID-19 patients using metagenomic and metatranscriptomic sequencing, identifying correlations between microbial composition, gene function, and disease severity.

bioRxiv · Nov 8, 2021 · PreprintBioinformatics