Early gonadotoxic effects of cyclophosphamide on the prepubertal testis and the feasibility of reducing toxicity through combined antioxidant therapy
Amirhessam Eskafi Noghani, Arturo Reyes Palomares, Xia Hao, Roudabeh Mohammadi, Arian Lundberg, Kenny A. Rodriguez-Walberg
This study identifies early gonadotoxic effects of cyclophosphamide on prepubertal testes and shows antioxidant co-treatment can reduce toxicity without compromising anticancer efficacy.
Reproductive Toxicology · Dec 29, 2025Peer-reviewedPharmacology & Toxicology