TOP the Transcription Orientation Pipeline and its use to investigate the transcription of non-coding regions: assessment with CRISPR direct repeats and intergenic sequences.
Kimberley Houenoussi, Roudaina Boukheloua, Jean‐Philippe Vernadet, Daniel Gautheret, Gilles Vergnaud, Christine Pourcel
The paper introduces TOP, a pipeline to determine transcription orientation of sequences using RNA-Seq data, validated on CRISPR repeats and small RNAs in Staphylococcus aureus.
bioRxiv · Jan 15, 2020 · PreprintBioinformatics