HIV-1 gp120 impairs spatial memory through CREB
Jenny Shrestha, Maryline Santerre, Charles N. S. Allen, Sterling P. Arjona, Ruma Mukerjee, Jin Park, Asen Bagashev, Ying Wáng, Marcus Kaul, Jeannie Chin, Bassel E. Sawaya
This study shows HIV-1 gp120 impairs spatial memory by inhibiting CREB activity, leading to mitochondrial dysfunction and synaptic plasticity loss.
bioRxiv · Oct 20, 2020 · PreprintNeuroscience