Molecular dynamic simulations to investigate the structural impact of known drug resistance mutations on HIV-1C Integrase-Dolutegravir binding
Rumbidzai Chitongo, Adetayo Emmanuel Obasa, Sello Given Mikasi, Graeme Brendon Jacobs, Ruben E.A. Cloete
This study uses molecular dynamics simulations to analyze how known drug resistance mutations affect the structure and binding of HIV-1C Integrase with Dolutegravir.
PLoS ONE · May 7, 2020Peer-reviewedBioinformatics