Spatiotemporal Heterogeneity of HPV Integration Architectures Drive Oncogenic Features of Oropharyngeal Cancer
Wenjin Gu, Apurva Dhanesh Bhangale, Xiaomeng Du, Xinyi Deng, Elizabeth U Gensterblum-Miller, Jordan Currie, Collin V. Brummel, Vital Nyabashi, Marisa Buchakjian, Keith A. Casper, Steven E Chinn, David Forner, Kelly Michele Malloy, Michelle L. Mierzwa, Mark E Prince, , John Chad Brenner
The paper characterizes HPV integration structures in oropharyngeal cancer and links Type2 integration to oncogenic features and aggressive tumor behavior.
bioRxiv · Oct 10, 2026 · PreprintBioinformatics