Single-Cell Analysis of Microglia and Monocyte Dynamics Uncover Distinct TNF-a-driven Neuroimmune Signatures after Intracerebral Hemorrhage
Yuki Kawamura, Conor W. Johnson, Jonathan Howard DeLong, Lucas Paulo de Lima Camillo, Sofia E. Velazquez, Munetomo Takahashi, Hannah E. Beatty, Ryan Herbert, Branden John Cord, Charles Christian Matouk, Michael Askenase, Lauren Hachmann Sansing
The paper uses single-cell transcriptomics to study microglia and monocyte dynamics after ICH, finding TNF signaling drives early monocyte activation and is linked to better neurological outcomes.
bioRxiv · Dec 24, 2024 · PreprintBioinformatics