Lauren Hachmann Sansing

Proteomic and Transcriptomic Differences in Ischemic Stroke Patients with Atrial Fibrillation Versus Carotid Atherosclerosis

The paper identifies proteomic and transcriptomic differences between ischemic stroke patients with atrial fibrillation and carotid atherosclerosis using integrated multi-omics analyses.

The Ethnic/Racial Variations of Intracerebral Hemorrhage Genetics (ERICH-GENE) Study Protocol

ERICH-GENE collects and analyzes genomic and neuroimaging data from over 10,000 multi-ethnic ICH cases to identify genetic risk factors and trans-ethnic variation in ICH.

Single-Cell Analysis of Microglia and Monocyte Dynamics Uncover Distinct TNF-a-driven Neuroimmune Signatures after Intracerebral Hemorrhage

The paper uses single-cell transcriptomics to study microglia and monocyte dynamics after ICH, finding TNF signaling drives early monocyte activation and is linked to better neurological outcomes.

Single-nucleus RNA sequencing of human periventricular white matter in vascular dementia

This study uses single-nucleus RNA sequencing to analyze periventricular white matter in vascular dementia, identifying increased heat shock protein responses as a conserved feature across cell types.

VEGF-C promotes brain-derived fluid drainage, confers neuroprotection, and improves stroke outcomes

This study shows that VEGF-C overexpression enhances brain fluid drainage, provides neuroprotection, and improves stroke outcomes in mice.