Additive framework of hormonal waves explains species and age differences in circadian intraocular pressure rhythm
Keisuke Ikegami, Ryo Fujie, Fumito Mori, Shinobu Yasuo
The paper develops a mathematical framework explaining circadian intraocular pressure (IOP) rhythms through the additive interaction of glucocorticoid and norepinephrine signals, showing it accounts for species differences and age-related changes.
bioRxiv · Oct 21, 2025 · PreprintPhysiology