Mechanism of action of rigosertib does not involve tubulin binding
S. J. Baker, S. C. Cosenza, S. Athuluri-Divakar, M. V. R. Reddy, R. Vasquez-Del Carpio, R. Jain, A. K. Aggarwal, E. P. Reddy
This paper investigates the mechanism of action of rigosertib and finds that it does not involve tubulin binding, as clinical grade rigosertib lacks the impurity responsible for this activity.
bioRxiv · Dec 12, 2019 · PreprintCancer Biology