Structure of Dimeric Lipoprotein Lipase Reveals a Pore for Hydrolysis of Acyl Chains
This paper determines the structure of active dimeric lipoprotein lipase (LPL) using cryoEM, revealing a hydrophobic pore for unidirectional fatty acid release and revising previous models of LPL function and dimerization.
bioRxiv · Mar 21, 2023Biophysics