Clathrin’s adaptor interaction sites are repurposed to stabilize microtubules during mitosis
A. Rondelet, Y.-C. Lin, D. Singh, A. T. Porfetye, H. C. Thakur, A. Hecker, P. Brinkert, N. Schmidt, S. Bendre, F. Mueller, P. O. Widlund, T. Bange, M. Hiller, I. R. Vetter, A. W. Bird
This paper identifies a novel role of clathrin in stabilizing microtubules during mitosis by repurposing its adaptor interaction sites to recruit GTSE1, which inhibits MCAK and supports chromosome congression.
bioRxiv · Aug 31, 2019Cell Biology