Aging-Associated Decrease in the Histone Acetyltransferase KAT6B Causes Myeloid-Biased Hematopoietic Stem Cell Differentiation
E. S. Khokhar, S. Borikar, E. Eudy, T. Stearns, K. Young, J. Trowbridge
This study shows that aging reduces KAT6B, an epigenetic regulator, leading to myeloid-biased differentiation of hematopoietic stem cells.
bioRxiv · Jun 22, 2019Cell Biology