The TTLL10 polyglycylase is stimulated by tubulin glutamylation and inhibited by polyglycylation
S. Cummings, Y. Li, J. Spector, C. Kim, A. Roll-Mecak
This study identifies substrate preferences and regulatory mechanisms of TTLL glycylases, showing how tubulin glutamylation and polyglycylation influence TTLL10 activity and microtubule modification.
bioRxiv · Mar 31, 2024 · PreprintBiochemistry