Sex Differences in Oncogenic Mutational Processes
C. H. Li, S. D. Prokopec, R. X. Sun, F. Yousif, N. Schmitz, P. C. Boutros, PCAWG Molecular Subtypes and Clinical Correlates Working Group, ICGC/TCGA Pan-Cancer Analysis of Whole Genomes Network
This study analyzes sex differences in whole genome mutational processes across 1,983 tumors from 28 subtypes, revealing sex-biased mutations in coding and non-coding regions and mutational signatures.
bioRxiv · Jan 28, 2019Cancer Biology