Ultra high diversity factorizable libraries for efficient therapeutic discovery
Z. Dai, S. D. Saksena, G. Horny, C. Banholzer, S. Ewert, D. K. Gifford
The paper designs factorizable libraries for therapeutic discovery using an optimization method called SAPS to generate diverse and efficient antibody CDR-H3 sequences.
bioRxiv · Jan 17, 2022 · PreprintBioengineering