The tooth on-a-chip: a microphysiologic model system mimicking the pulp-dentin interface and its interaction with biomaterials
C. Miranda Franca, A. Tahayeri, N. Sousa Rodrigues, S. Fedorsian, R. Puppin-Rontani, J. Ferracane, L. E. Bertassoni
The paper develops a tooth-on-a-chip model to study dental pulp cell responses to biomaterials, finding that HEMA > SB > PA are cytotoxic and cells show higher metabolic activity on-chip than off-chip.
bioRxiv · Aug 28, 2019 · PreprintBioengineering