Roles of the second-shell amino acid R266 in other members of the MLE subgroup of the enolase superfamily
D. P. Truong, S. Fults, C. Davila, J. P. Huddleston, D. Brock, M. Zhu, J.-P. Pellois, K. G. Hull, D. Romo, F. M. Raushel, M. E. Glasner
This study examines how the R266 residue affects NSAR and OSBS activities in multiple NSAR/OSBS subfamily members, showing that its impact varies due to sequence context and epistasis.
bioRxiv · Mar 3, 2022 · PreprintBiochemistry