Model-based assessment of the Role of Uneven Partitioning of Molecular Content on Heterogeneity and Regulation of Differentiation in CD8 T-cell Immune Responses
S. Girel, C. Arpin, J. Marvel, O. Gandrillon, F. Crauste
The paper uses a multiscale model to show that uneven molecular partitioning during CD8 T-cell division regulates differentiation and promotes memory cell generation.
bioRxiv · Jun 12, 2018Immunology