Accurate allele frequencies from ultra-low coverage pool-seq samples in evolve-and-resequence experiments
S. Tilk, A. O. Bergland, A. Goodman, P. Schmidt, D. Petrov, S. Greenblum
This paper introduces a method to accurately estimate allele frequencies from low-coverage pool-seq data in evolve-and-resequence experiments using haplotype inference.
bioRxiv · Sep 20, 2019Evolutionary Biology