Author

S. H. Leppla

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:bacteria (other)· 1 Assay:imaging· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Gangwal· 1 shared A. P. Pomerantsev· 1 shared C. c. keshavam· 1 shared C. Merritt· 1 shared D. Paliga· 1 shared E. M. Chun· 1 shared L. K. Singh· 1 shared M. Gupta· 1 shared

Activity by Year

2021-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperMicrobiology

A. Gangwal

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2 papers

Recent·Most cited

Bacillus anthracis chain length, a virulence determinant, is regulated by a transmembrane Ser/Thr protein kinase PrkC

M. Gupta, Y. Singh, N. Dhasmana, N. Kumar, A. Gangwal, C. c. keshavam, L. K. Singh, N. Sangwan, P. nashier, S. biswas, A. P. Pomerantsev, S. H. Leppla

This study identifies PrkC, a transmembrane Ser/Thr kinase in B. anthracis, as a regulator of bacterial chain length, which impacts virulence and pathophysiological outcomes.

Journal of Bacteriology · May 7, 2021Peer-reviewedMicrobiology

Direct imaging of anthrax intoxication in animals reveals shared and individual functions of CMG-2 and TEM-8 in cellular toxin entry

C. Merritt, E. M. Chun, R. J. Fattah, M. Moayeri, D. Paliga, S. Neumann, R. Heumann, S. H. Leppla, T. H. Bugge

The paper develops a live animal imaging assay to visualize anthrax toxin entry via CMG-2 and TEM-8, revealing tissue-specific receptor functions.

bioRxiv · Jan 22, 2021 · PreprintPathology