Comparative gene expression in cells competent in or lacking DNA-PKcs kinase activity following etoposide exposure reveal differences in gene expression associated with histone modifications, inflammation, cell cycle regulation, Wnt signaling, and differentiation.
S. I. Ali, M. J. Najaf-Panah, J. Sena, F. D. Schilkey, A. K. Ashley
The paper compares gene expression in cells with and without DNA-PKcs kinase activity after etoposide exposure, revealing differences in inflammation, cell cycle, and differentiation pathways.
bioRxiv · Sep 17, 2020 · PreprintCancer Biology