Structural basis of DNA targeting by a transposon-encoded CRISPR-Cas system
T. Halpin-Healy, S. Klompe, S. Sternberg, I. Fernandez
The paper determines the structure of a TniQ-Cascade complex using cryo-EM, revealing how it targets DNA and facilitates transposition by bacterial transposons.
Nature · Dec 18, 2019Peer-reviewedBiophysics